REFINE TECHNOLOGY

Refine Technology manufactures and sells worldwide The ATF™ System, a best-in-class cell retention device, which is principally known for being able to routinely generate extremely high cell concentrations.

Used in research through to large scale commercial manufacturing, the ATF System also provides many other opportunities to improve your bioprocess at every stage of your biological product pipeline.

Facility

Factory of the future
Economic Analysis / Cost of Goods
Risk Management

Stage

Pre-Clinical
Process Development
Phase I/II
Phase III / Commercial

Applications

Protein production
Transient Expression
Vaccines
Microcarriers
Concentrated Perfusion
Hybrid Production

Cell/Product type

Stem Cells
Adherent cells
CHO/PER.C6 Suspension cells
Insect cells
Virus/VLPs
Cells as product
Microbial / Yeast

Process

Overview
Upstream
Downstream
Monitoring & Control
Process & Comparisons

Technical

Alternating Tangential Flow Technology
ATF System Product Information
Hollow Fiber and Screen Modules
Bioreactor checklist
Connecting to your bag, tank or reactor

Unit Operations

Cell Banking & Seed Expansion
Cell Culture
Fermentation
Media Exchange
Harvest / Clarification
Filtration (UF/DF)

Support

Product & Application Support
Maintenance & Breakdown Service
Installation & IQ/OQ
Literature & documentation
Contact support information

REFINE NEWS

Leverage knowledge to promote and expand continuous processing in the biotech industry

View >>

Thermo Fisher Scientific and Refine Technology
Partner for Expanded Capabilities

Enables Optimal Results for Large Scale Bioprocessing
Expands Open Architecture Platform for Both Companies

View >>

ATF SYSTEM SELECTOR TOOL

Please click here to visit the ATF System Selector Tool

REFINE SHOWCASE

Please click here to view all the latest articles

RECRUITMENT

DOWNLOADS