The CORe™ Culture Optimization Reactor is a stand-alone and cost effective bioreactor system that is compact and flexible in design. The convenient on-board controls and touch screen display eliminates the need for a bulky external controller thus saving valuable bench space and facilitating ease of portability. The unit can be operated on a bench, in a laminar flow hood or even on a desk. Data is easily exported via an ethernet connection into common analysis programs. The addition of multiplexing capabilities will be forthcoming.

The pre-sterilized single use vessel offers a working capacity of 35-100ml which allows significant savings in media costs without compromising performance. Sensors for temperature, pH and DO are all in wall, minimizing contamination risks and interference from the inserts. The only product contact surface is the impeller and shaft which also contains the sparger allowing for gas additions including O2, CO2, N2 and air. Various impeller and sparger designs may be custom ordered to fit user requirements.

The CORe™ Mini Bioreactor includes four pumps with an option of up to eight pumps for flexible media handling. Sampling can be performed from both top and bottom ports which facilitate access to and from the vessel. They also provide a convenient connection to a cell concentration device. It can be configured for batch, fed batch or continuous operation.

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Culture Optimization Reactor system designed with the capabilities of a larger system but at a much lower cost and smaller footprint

  • Flexible, single-use vessel design is free of interfering inserts and probes
  • Operational control driven through on-board software interface
  • Bioreactor pump customization options allow high level of experimental control and flexibility
  • Ideal for stem cell research and development, cell and tissue culture, seed development, educational applications and more
  • Supports batch, fed batch and continuous bioprocess applications with addition of a cell separation device

Key Features

  • Reduced media consumption
  • Single-use culture vessel
  • In Wall sensors for pH, DO and temperature
  • Compact, lightweight and portable design
  • Easily moved from bench to laminar flow hood
  • Bottom port for sampling or connection to perfusion system
  • Touch-screen user interface
  • Data can be easily exported to common data analysis programs
  • Customization options:
    – Vessel port configuration
    – Pumps and pump options
    – Sparger
    – Impeller

Applications

Aeration through agitation shaft with customizable impeller and sparger

Customizable head port design for experimental flexibility

Optical sensors limit media contact materials and minimize contamination

  • Stem cell research

  • Media optimization studies

  • Mammalian cell culture

  • Process optimization and development

  • Batch, fed batch and continuous processing

Specifications

Size: 4.2 x 8.0 x 13.3 in (10.6 x 20.6 x 33.8 cm)

Weight: 2.5 lbs (1.14 kg)

Power: 100 to 240 volts, 50 to 60 Hz

Operating Temp Range: 18° to 28° C

Ports: 8

Pump: 4 standard, option for 8

Vessel Material: Single-use polycarbonate

Vessel Volume: 35–100mL

Aeration: Through impeller shaft

Gases: CO2, N2, O2, air

Temperature Sensor: external RTD (100 Ω)

pH Probe: In Wall, optical non-fluid contact (pH 4-8)

DO Probe: In Wall, non-fluid contact

Impeller: 10–200 RPM (can be customized)

Software Interface: Ethernet

26 Chapin Road Unit 1107
PO Box 691
Pine Brook, NJ 07058
Tel: 973-952-0002 | Fax: 973-952-0211
orders@refinetech.com