REFINE TECHNOLOGY

Refine Technology manufactures and sells worldwide The ATF™ System, a best-in-class cell retention device, which is principally known for being able to routinely generate extremely high cell concentrations.

Used in research through to large scale commercial manufacturing, the ATF System also provides many other opportunities to improve your bioprocess at every stage of your biological product pipeline.

Facility

Factory of the future
Economic Analysis / Cost of Goods
Risk Management

Stage

Pre-Clinical
Process Development
Phase I/II
Phase III / Commercial

Applications

Protein production
Transient Expression
Vaccines
Microcarriers
Standard Concentrated Perfusion
Concentrated Fed-Batch
Hybrid Production

Cell/Product type

Stem Cells
Adherent cells
CHO/PER.C6 Suspension cells
Insect cells
Virus/VLPs
Cells as product
Microbial / Yeast

Process

Overview
Upstream
Downstream
Monitoring & Control
Process & Comparisons

Technical

Alternating Tangential Flow Technology
ATF System Product Information
Hollow Fiber and Screen Modules
Bioreactor checklist
Connecting to your bag, tank or reactor

Unit Operations

Cell Banking & Seed Expansion
Cell Culture
Fermentation
Media Exchange
Harvest / Clarification
Filtration (UF/DF)

Support

Product & Application Support
Maintenance & Breakdown Service
Installation & IQ/OQ
Literature & documentation
Contact support information

REFINE NEWS

Development of a robust, easy-to-use platform for high-density cell cultivation

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PBS Biotech® and Refine Technology Provide Powerful Bioreactor and Perfusion Application for Biotech Users.

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ATF SYSTEM SELECTOR TOOL

Please click here to visit the ATF System Selector Tool

REFINE SHOWCASE

Please click here to view all the latest articles

RECRUITMENT

DOWNLOADS

EVENTS

  • Please join us at the following conferences & exhibitions:

Feb
15

February 15 - February 16, 2012
5th Annual BioInnovation Leaders Summit 2012
London

Feb
27

February 27 - February 29, 2012
4th Annual Disposable Solutions for Biomanufacturing
Brussels

Apr
02

April 02 - April 04, 2012
ISBioTech 2nd Annual Meeting
Virginia

Apr
11

April 11 - April 13, 2012
World Vaccine Congress 2012
Washington